Up and Down
the Middle Mississippi River
Regional Guides to Illinois and Missouri
on the Great River Road

French Colonial Country
The region along the Mississippi River south of St. Louis is French Colonial Country. Once the administrative center for this region of the Louisiana Territory the area offers visitors a unique glimpse into this time period. Unique homes can be found in Ste. Genevieve’s historic district. Across the Mississippi River in Randolph County sites include the Pierre Menard Home and Fort de Chartres. The area has many specialty shops, antique shops, Bed & Breakfasts and restaurants.
St. Louis, Missouri
Established in 1763 as a French fur trading outpost, St. Louis has a long been considered the "Gateway to the West." It’s rich history and the diverse amenities it enjoys as a major metropolis make it an exciting destination for visitors.
Meeting of the Great Rivers Scenic Byway
One of America's newest Scenic Byways, the Great River Road travels along the Mississippi River along picturesque limestone bluffs.  Attractions include the starting point of Lewis & Clark's epic journey and Illinois' largest state park - Pere Marquette State Park. Visit the real river towns of Alton, Elsah and Grafton or take a side trip to Calhoun County.
Historic St. Charles
Located a short distance west of St. Louis, easily accessible by I-70 is Missouri's the bustling town of St. Charles. Visit the historic downtown district with a large variety of eateries and specialty shops. This district comes alive on weekends throughout the year as the area is host to numerous events. The new Lewis & Clark Boat House and Nature Center is just part of the attractions that make St. Charles a site on the National Lewis & Clark Historic Trail.
Hannibal, Missouri
Known best as the home of Mark Twain, Hannibal provides it visitors with a glimpse into what it was like living along the river in the 19th century. Visitors can ride a real riverboat, visit Missouri's oldest show cave and enjoy the outdoors at Missouri's largest state park. There is plenty of shopping and lodging around town and a full schedule of events throughout the year.

 

 
  Regional Guides
to the Middle Mississippi River Valley
 
 
Meeting of the Great Rivers
National Scenic Byway

Ste. Genevieve &
French Colonial Country

Gateway to the West
S. Louis & St. Louis County
        


Meeting the Missouri
Historic St. Charles County
 

The Lincoln Hills Region
Northeast Missouri
  
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Images - Elsah, Illinois and Owl109 Enterprises, St. Louis, MO