Directions to 
Hillsboro
Jefferson County, Missouri

FROM St. Louis and points north and west
Take I-55 South to CR-Z (Pevely Exit)
Take CR-Z west to CR-A
Take CR-S west MO-21
Take MO-21 south into Hillsboro

FROM Springfield, IL and points north and east
Take I-55 south to I-255
Take I-255 South across the Mississippi River to I-55
Take I-55 South to CR-Z (Pevely Exit)
Take CR-Z west to CR-A
Take CR-S west MO-21
Take MO-21 south into Hillsboro

FROM Memphis and points south
Take I-55 North to CR-Z (Pevely Exit)
Take CR-Z west to CR-A
Take CR-S west MO-21
Take MO-21 south into Hillsboro

 

 
 

 Regional Guides
to the Middle Mississippi River Valley


Ste. Genevieve &
French Colonial Country

Meeting of the Great Rivers
National Scenic Byway


Meeting the Missouri
Historic St. Charles County


The Lincoln Hills Region
Northeast Missouri

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