Regions of the
Middle Mississippi River Valley

greatriverroad.com covers 47 counties in 6 states that border the Mississippi River. Our coverage. Readers can navigate and explore greatriverroad.com selecting a particular region. Regions from north to south are the Tri-State Area, Missouri’s Lincoln Hills, The Meeting of the Great Rivers Scenic Byway, Meeting the Missouri (Saint Charles County, Metropolitan Saint Louis, French Colonial Country, Meeting the Ohio River, and the Upper Delta Region.

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THE TRI-STATE REGION
IOWA, MISSOURI & ILLINOIS

The Tri-State region includes Lee County in southwest Iowa, the northwestern Missouri counties of Lewis and Clark, and the western Illinois counties of Hancock, Adams, and Pike. Notable communities include Quincy, Keokuk, Fort Madison, and Nauvoo.

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MISSOURI’S LINCOLN HILLS
IN NORTHWESTERN MISSOURI

Missouri’s Lincoln Hills includes the northwestern Missouri counties of Ralls, Marion, Pike and Lincoln, Notable communities include Hannibal, Clarksville, Louisiana, and Elsberry.

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THE MEETING OF
THE GREAT RIVERS SCENIC BYWAY AREA

The Meeting of the Great Rivers Scenic Byway Area coverage includes the Illinois counties of Jersey, Calhoun, and Madison. Notable communities covered are Alton, Grafton, Elsah, Collinsville, Edwardsville, and Hartford.

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MEETING THE MISSOURI RIVER
SAINT CHARLES COUNTY, MISSOURI

The Meeting the Missouri River covers Saint Charles County, Missouri which encompasses the confluence of the Missouri and Mississippi Rivers. Notable communities include Saint Charles, Saint Peters, and Augusta.

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GATEWAY TO THE WEST
ST'. LOUIS AND ST LOUIS COUNTY

The Metropolitan Saint Louis Area includes coverage of Saint Louis, Missouri and the communities of Saint Louis County.

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FRENCH COLONIAL COUNTRY

The region along the Mississippi River south of St. Louis is French Colonial Country. The area was first colonized by the French in 1699 and includes the Missouri Counties of Sainte Genevieve and Jefferson and the Illinois Counties of Saint Clair, Monroe, and Randolph. Notable communities include Sainte Genevieve, Kimmswick, Belleville, Waterloo, Columbia and Chester.

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MEETING THE OHIO RIVER

After the Mississippi River passes St. Louis it begins to change character. When the Mississippi River meets the Ohio River at Cairo, Illinois it is halfway on its journey to the sea. greatriverroad.com’s coverage includes the Missouri Counties of Cape Girardeau, Perry, Scott, and Mississippi, the Illinois Counties of Jackson, Union, and Alexander, and all of Western Kentucky. Notable communities include Cape Girardeau, Sikeston, Murphysboro, Carbondale, Cairo, and Wyckliffe.

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THE UPPER DELTA REGION

The Upper Delta Region of the Middle Mississippi River Valley is where the river really meets the south. The area includes the Bootheel region of Missouri, the scene of the famous 1811-1812 New Madrid earthquakes. In northeast Arkansas greatriverroad.com departs from its normal rule of only covering counties that border the river by adding coverage of the Crowley’s Ridge Scenic Byway with its Ozark like terrain and many state parks and attractions.